A school bus crash near the southern Arizona city of Tucson has left several students from a different part of the state seriously injured and closed a major interstate. The Arizona Department of Transportation told USA TODAY that Interstate 10 was closed in both directions around milepost 240 in Marana and that "there is no estimated time to reopen the highway.

Interstate 10 is closed in both directions in Pima County after a serious crash involving a school bus, according to the Arizona Department of Public Safety.

Three high school students and one adult suffered serious injuries when their school bus crashed in Tucson, Arizona, on Tuesday.

WEST PLAINS, Mo — 8 students were on board a West Plains school bus when it crashed Thursday morning, according to the district on social media. 8 students were on board the bus at the time of the accident with another vehicle.

Arizona Department of Public Safety officials say troopers responded to a school bus crash along Interstate 10, northwest of Tucson.

Huntsville City Schools says no students were injured after what the system called a minor bus accident on Mastin Lake Road.