Carbon monoxide may help explain the long-observed but perplexing association between smoking and a lower risk for Parkinson’s disease.

Parkinson’s disease is caused by decreased dopamine activity in a brain region. It often has no identifiable trigger, but known triggers include genes, head trauma, and environmental toxins.

A new study by investigators from the Mass General Brigham Neuroscience Institute has identified common genetic variants in the MC1R gene as markers of faster motor decline in people with Parkinson's disease (PD).

Parkinson’s disease is significantly less common among people who smoke cigarettes. It’s a paradox that has perplexed researchers for decades, drawing speculation that tobacco smoke somehow protects the brain from developing the neurodegenerative condition.

Parkinson's disease affects more than 1 million Americans, and celebrities from Michael J. Fox to Billy Connolly have raised awareness for it in big ways.

Exposure to higher levels of exhaled carbon monoxide is associated with a lower risk of Parkinson’s disease, even among people who have never smoked, a study suggests.1 Examining data from 512 000 adults,

Independent Safety Monitoring Committee recommends advancement to Cohort 2 following blinded review of Cohort 1 safety and tolerability data – - Pharmacokinetic observations at the lowest dose evaluat