Soluble adenylyl cyclase (sAC) represents a pivotal component of intracellular signalling, distinct from the widely studied transmembrane adenylyl cyclases. Regulated by bicarbonate and calcium rather ...
Adenylyl cyclases (ACs) are pivotal enzymes that catalyse the conversion of ATP to cyclic AMP (cAMP), a ubiquitous second messenger integral to the transduction of extracellular signals. In mammalian ...