The Bills have elevated RB Frank Gore Jr. and WR Greg Dortch from the practice squad for tonight's game against the Lions. Gore is likely a one-for-one replacement for third-down running back Ty Johnson, who was limited at practice all week with a hamstring injury. Johnson has been dealing with the injury for over a month.

Josh Allen made NFL history, Joe Brady accomplished a Bills first and Buffalo scored 41 points in the first regular-season game at its new stadium.

The Detroit Lions got humbled in the first half of Thursday Night Football, trailing 27-10 to the Buffalo Bills. The Lions needed to figure out what went wrong if they want to turn things around, and head coach Dan Campbell was asked what went wrong in the first half.

The Buffalo Bills host the Detroit Lions in their first game at their new home, Highmark Stadium. Here are all the highlights from Bills vs. Lions in Buffalo.

Kalshi offers Bills vs. Lions prediction markets for Thursday Night Football, including Buffalo by 1-6 points and player props for Sam LaPorta and Josh Allen

Joe Brady is only two games into his first season with the Buffalo Bills , yet he has already hit an impressive milestone. Brady steered the Bills to a 10-point victory over the Detroit Lions, 41-31,

Here's our fantasy football start or sit advice for Buffalo Bills wide receivers Khalil Shakir and Joshua Palmer and kicker Tyler Bass in Week 2.