Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology.

Myocardial fibrosis is major pathological outcome after myocardial ischemia/reperfusion (MI/R) injury and a major risk factor for heart failure. MI/R injury induces cardiomyocyte damage or even death, ...

Northwestern Medicine scientists have discovered a way to regenerate damaged heart muscle cells in mice, a development that may provide a new avenue for treating congenital heart defects in children ...

Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year. Damage caused by these diseases is particularly difficult to repair, since ...

In a recent study led by Associate Professor Yoshinori Yoshida (Department of Cell Growth and Differentiation) and published in Communications Biology, a team of researchers identified CD151 as a ...

Decoding the cardiac cellular universe: primary cell resources for dissecting heart microenvironment-driven disease ...

Novel technology returns cardiomyocytes to a stem cell-like state to promote their proliferation and regeneration in an in vitro study. Researchers at the University of Houston (TX, USA) have ...

Nine out of every ten patients in a Chinese heart failure trial showed significantly ...

The heart is like a high-octane engine. Fueled by fatty acids, cardiomyocytes have abundant mitochondria to rev up ATP production through oxidative phosphorylation and keep the engine humming. However ...

“For decades, researchers have been trying to find the specialized cells that make new muscle cells in the adult heart, and we think that we have found that cell,” Hesham Sadek, the senior author of ...