Emerging mRNA vaccine strategies target cancer and pathogenic viruses in potent new ways

The technology that gave the world mRNA COVID vaccines is being tested in a variety of new ways, and emerging research ...
Medical Xpress

Targeted centrosome inheritance during CD8⁺ T cell division plays role in memory precursor cell generation: Study

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells. CD8 + T ...

Hidden thymus step may prime cancer-killing T cells earlier than expected

Researchers at Mayo Clinic have uncovered a previously hidden step in how the immune system prepares to fight cancer, a ...
The American Journal of Managed Care

Clonally Expanded CD8+ T Cells May Play Role in Alopecia Areata

Clonally expanded CD8+ T cells are key drivers of alopecia areata, mediating epithelial cell death and immune infiltration. JAK inhibitors are approved for AA treatment, but recurrence is common, ...
The Manila Times

Treos Bio Presents New Translational Data Showing PolyPEPI1018 Plus Anti-PD-L1 Immunotherapy Remodels the Tumor Immune Microenvironment in MSS Colorectal Cancer

ESMO GI poster highlights increased intratumoral CD8+ T-cell infiltration, PD-L1 expression, expansion of tumor-reactive TCR clonotypes and association with clinical outcome ...
Kaleido Scope

Reinvigorating exhausted T cells in cancer and chronic viral infections

Killer immune cells destroy cancer cells and cells infected by virus. These CD8 + T cells are activated after detection of viral infection or growth of “non-self” tumor cells. However, in chronic ...