In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation ...

Gap junctions are specialised intercellular channels formed by hexameric assemblies of connexin proteins in vertebrates, and related pannexin channels that mediate paracrine signalling. Connexin ...

Northwestern Medicine investigators have discovered new mechanisms underlying cellular adhesion and repair, findings that could inform the development of new therapeutics that boost cellular repair ...

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation ...

Cells and tissue are known to undergo significant irreversible deformations during processes such as tissue formation and embryo development. A research team led by Professor Yuan Lin from the ...

Epithelial tissues form selective barriers and undergo complex remodelling throughout embryogenesis and organogenesis. Central to these processes are specialised intercellular junctions—tight ...

Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell ...