Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...

Cell-free protein synthesis (CFPS) harnesses the molecular machinery of living cells in an open in vitro environment to produce proteins without the constraints of cell viability. Derived from crude ...

AI-driven drug discovery can be accelerated by combining cell-free expression with purification-free SPR for faster ...

Researchers at Leipzig University and Martin Luther University Halle-Wittenberg have investigated a previously unknown process that occurs during protein synthesis in the cell. They examined how ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Physicists apply Landau theory and spherical harmonics to show that non-viral protein nanocontainers self-assemble as quasi-crystalline mosaics on spherical surfaces, ...

AI can rapidly generate new protein binders, but wet-lab validation remains a major bottleneck. Combining cell-free protein ...

A protein whose failure lies at the heart of a devastating childhood neurodegenerative disorder has turned out to be a long-sought enzyme in one of the cell’s most obscure lipid-making pathways. In t ...