During cell division microtubules capture chromosomes by binding to the kinetochore assembled in the centromeric region of chromosomes. In mitosis sister chromatids are captured by microtubules ...
The two proteins KNL2 and CENP-C are crucial for the correct separation of chromosomes during cell division. To dock to the centromere, the newly described additional binding regions (DNA-b) to the ...
University of Rochester research reveals that centromeres, which are responsible for proper cell division, can rapidly reorganize over short time scales. The discovery involves an intricate and ...
Early studies revealed that centromeric DNA and the centromere-specific histone variant cenH3 both evolve rapidly, leading to dramatic differences in centromeric organization even between closely ...
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