The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...

A team of Chinese scientists has uncovered a hidden 3D structure in rice DNA that allows the crop to grow more grain while using less nitrogen fertilizer. The finding, published in Nature Genetics by ...

A 52,000-year-old woolly mammoth carcass was so well preserved, scientists were able to determine the 3D structure of the prehistoric creature's genetic code, a first-of-its-kind study shows. "Until ...