The latest NFL power rankings show the Detroit Lions have more questions than answers entering Week 2.

Detroit Lions Tuesday injury report ahead of Buffalo Bills game.

Rookie right tackle Blake Miller (knee) and left guard Christian Mahogany (hip) were listed as non-participants at Tuesday’s walkthrough. As always, when it’s a walkthrough instead of practice, the Lions provide an estimated report.

The Detroit Lions open their 2026 NFL season versus the Saints. Follow live score updates, highlights, injury news, key plays and instant analysis.

The Detroit Lions narrowly avoided disaster against the New Orleans Saints on Sunday. Here are our position-by-position grades from the overtime win.

You understand what you’re getting ready to face and why wouldn’t they test us there? We would do the same thing.”

The New Orleans Saints travel to take on the Detroit Lions in the season opener for both teams at noon on Sunday at Ford Field. This is the place to keep up with the score and live updates. Following a strong finish to the 2025 campaign, Tyler Shough will get his first season-opening NFL start at quarterback for the Saints.

Detroit Lions want to get Jameson Williams, Isaac TeSlaa more targets.