Phys.org

Locusts bypass classical molecular pathway to process smells and pheromones, study reveals

Animals depend on their sense of smell to locate food, identify mates and evade danger. In mammals, olfactory perception typically relies on G protein–coupled receptor (GPCR) pathways. Insects, by ...

By making key signaling molecules called β-arrestins into druggable targets, scientists crack long-standing challenge

To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...
EurekAlert!

Researchers use NMR, mathematical modelling and simulations to reveal how a tryptophan-rich allosteric communication network helps activate a major drug target receptor

Computational analysis using rigidity-theory indicates that activation of the human adenosine A 2A receptor (shown here) is regulated by long-range allosteric communication pathways (highlighted in ...
Medical Xpress

Chemical tool illuminates pathways used by dopamine, opioids and other neuronal signals

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons. These chemicals are among a wide variety of signals ...