Scientists at Duke-NUS Medical School and the National University Health System (NUHS), together with an international team ...

Medically reviewed by Qin Rao, MD Intestinal metaplasia is a condition involving cell changes in the upper digestive tract lining.Helicobacter pylori infection is the greatest risk factor for ...

The study of gastric cancer and its precursors, such as metaplasia, remains critical in addressing one of the leading causes of cancer‐related mortality worldwide. This research field is focussed on ...

Gastric cancer often develops through a gradual sequence of changes, beginning with superficial gastritis and advancing through chronic atrophic gastritis, intestinal metaplasia, and precancerous ...

Clinicians can help reduce gastric cancer incidence and mortality in high-risk groups through endoscopic screening and surveillance of precancerous conditions, such as gastric intestinal metaplasia ...

Genetic mutations, oxidative stress, smoking, oral bacteria, and age-related blood mutations have been identified as early drivers of gastric cancer, offering new ways to predict risk and prevent ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this journey through a disease state contains ...

Please provide your email address to receive an email when new articles are posted on . H. pylori eradication is strongly encouraged for patients with gastric premalignant conditions. High-quality ...

The researchers initially characterized the colonization of multiple H. pylori strains in control mice or mice with genetically induced tissue metaplasia. Several of the tested strains could infect ...

Duke-NUS and NUHS scientists uncover a complex web of genetic, age-related and microbial factors that increase the risk of stomach cancer. Age-related blood cell mutations may trigger early changes in ...