Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going.

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During ...

Researchers in China have identified the MADS-box transcription factor MdAGL29 as a negative regulator of shoot branching in ...

Atherosclerosis develops when deposits known as plaques build up in the walls of blood vessels over many years. These plaques are particularly dangerous when they become unstable and rupture: Blood ...

The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions of life. Inside each cell, catalysts seek out the appropriate information from this ...

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of ...

Rosalind Franklin, James Watson and Francis Crick discovered the structure of DNA—that molecular blueprint for life—over 70 years ago. Today, scientists are still uncovering new ways to read it. In ...

A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene ...

While scientists have studied the molecular steps involved in gene expression for decades, many questions still remain about this fundamental process. To transcribe genes, RNA polymerase II (RNA Pol ...