SSRIs, SNRIs, NRIs, NDRIs, and SNDRIs ...

The story of SSRIs began by accident in the 1950s when doctors noticed that tuberculosis drugs lifted patients’ moods. This ...

A collage of a ball-and-stick model of a serotonin molecule, a sad-looking person, some drug capsules, and a brain Credit: Shutterstock/Madeline Monroe/C&EN For decades, doctors, neuroscientists, and ...

The combination may be lethal.

Shandong Quanzhong Biomedical Technology Co. Ltd. has synthesized monoamine transmitter reuptake inhibitors reported to be useful for the treatment of neurological disorders, depression, autism, pain, ...

Several medication options may help manage symptoms of post-traumatic stress disorder (PTSD). These include SSRIs (selective serotonin reuptake inhibitors), SNRIs (serotonin-norepinephrine reuptake ...

Neuroscientists recently identified molecular mechanisms in the brain that may explain why the active ingredient (fluoxetine) in selective serotonin reuptake inhibitors (SSRIs) sold under brand names ...

Serotonin reuptake inhibitors, particularly selective agents (SSRIs), are widely employed in the management of mood disorders and are increasingly recognised for their effects on blood clotting ...

Graphical Abstract: Antidepressant drugs act by directly binding to TrkB neurotrophin receptors. Source: Casarotto et al., 2021/open-access paper in Cell (CC BY 4.0) Key Points: A new study challenges ...

Impact of diabetes on respiratory infection risk and hospitalization following immune checkpoint inhibitor initiation in non–small cell lung cancer: A propensity-matched retrospective cohort analysis.

Reuptake inhibitors are a type of drug used to treat depression, anxiety, and other psychiatric conditions. They work by preventing neurotransmitters—the body’s chemical messengers—from being ...