Tuberculin skin test positivity exceeds interferon-gamma release assay positivity among healthcare workers and first ...

In adults with rheumatoid arthritis (RA), higher serum levels of interferon (IFN) alfa were linked to greater disease activity and autoantibody positivity; however, IFN-gamma showed no such link, and ...

Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer. The primary goal of this study was ...

Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new role for a protein called extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that ...

T cells have long been studied for their ability to target and eliminate tumor cells. In order for the T cells to do so, the tumors must express antigens not presented by healthy tissues, and the ...

Interferon gamma (IFN-γ) is a cytokine that induces a series of immune responses against viruses and tumors. The pro-apoptotic, anti-tumor and anti-proliferative actions of the cells are activated ...

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting ...

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds light on how interferon-gamma (IFN-y), an immune response-stimulating signaling molecule that helps activate immune ...

Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. Researchers at ...