Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided immunology for decades. The research found that when cancer cells shut down a ...

In a paradigm-breaking study, researchers have discovered a novel way the immune system, specifically T cells, attack their target cells, reshaping long-held assumptions in immunology and ...

A newly recognized set of T helper cells seems to guard against aging by eliminating harmful senescent cells. Their presence in supercentenarians suggests they may be a key to maintaining a healthier, ...

T cell immunity constitutes a central pillar of the adaptive immune response to SARS-CoV-2, acting in concert with antibodies to prevent severe disease. CD4⁺ helper T cells orchestrate antiviral ...

For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...