The insulin-like growth factor (IGF) system comprises two ligands (IGF-I and IGF-II), their cell-surface receptor (IGF1R) and a family of six high-affinity IGF-binding proteins (IGFBP-1 to ‑6), ...
Insulin-like growth factors (IGFs) and their associated receptors constitute a critical signalling axis in vascular biology, integrating metabolic cues with cellular growth, survival and repair ...
A research team revealed that insulin-like growth factor-binding protein 6 (IGFBP6) serves as a potential therapeutic target for suppressing endothelial inflammation and atherosclerosis. Their work ...
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