In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have ...

What the research is about Our intestine has a remarkable ability to repair themselves after injury. However, when ...

Attrition in the therapeutic pipeline can often be associated with the lack of translational efficacy from the pre-clinical phase to the clinic. Organoids demonstrate the significant potential to ...

People who are infected with chlamydia can transmit these bacteria to other people during unprotected sex. The pathogens usually cause no symptoms, or only mild symptoms at first, such as itching in ...

New culture system enables the stable, scalable, and low-cost production of clinical-grade intestinal organoids, as reported by researchers from Science Tokyo. Whereas conventional organoid cultures ...

Attrition in the therapeutic pipeline is often linked to the gap in translational efficacy between the pre-clinical phase and clinical outcomes. Organoids offer strong potential for improving disease ...

Animal models have enabled us to learn an incredible amount of new information about human biology, health, and disease. But these animals can't always serve as a reliable example of the human body.

For the roughly 3 million Americans living with inflammatory bowel disease, the current treatment options tell a frustrating story. Anti-TNF biologics such as infliximab and adalimumab, the backbone ...

A team led by Prof. Dr. Dirk Haller has demonstrated for the first time that defective mitochondria cause injuries in the intestinal epithelium and influence the microbiome. In this microscopic image ...

Inflammatory bowel disease (IBD) and other intestinal disorders affect millions of people worldwide, often causing lasting damage to the lining of the gut. In severe cases, this damage can become ...