Kinesin-1 is a dynamic heterotetrameric assembly of two heavy and two light chains (KHC and KLC) that mediates microtubule-based intracellular transport of many different cargoes. The complex adopts a ...
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside ...
The structure of a key part of the machinery that allows cells to divide has been identified by researchers, opening new possibilities for throwing a wrench in the machine and blocking runaway cell ...
This is a preview. Log in through your library . Abstract During the first cell cycle, the vegetal cortex of the fertilized frog egg is translocated over the cytoplasm. This process of cortical ...
Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping neurons healthy: ...
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Scientists map kinesin-2 tail structure to understand cargo binding
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?
Learn more about an important cellular protein called kinesin from this video by the University of California San Francisco (UCSF), and Ron Vale Ph.D., a UCSF researcher. Kinesin is a motor protein, ...
One of the hallmarks of cancer is the uncontrolled growth of cells that leads to tumours forming. Using chemotherapy that disrupts the machinery needed for cell division is commonly used to tackle ...
Researchers from the University of Tokyo and Juntendo University have identified a previously unknown structural domain in the motor protein kinesin-2 that enables precise cargo recognition in neurons ...
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