The noradrenergic nucleus locus coeruleus (LC) is a tiny cluster of cells located bilaterally in the pons just under the fourth ventricle. Despite its small size (it groups just 1,500 neurons on each ...

The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...

The locus coeruleus is a nucleus that controls attention, memory and alertness, but a study shows that it seems to weaken in later years. Older adults appear more easily distracted by irrelevant ...

Place a finger on the back of your skull, at a point roughly level with the tops of your ears. Here, deep beneath the hair, skin and bone, near a fluid-filled cavity in the root of your brain, lies a ...

A new study has linked signs of heightened arousal and reactivity -- a core symptom of posttraumatic stress disorder (PTSD) -- to overactivity of the locus coeruleus (LC), a brain region that mediates ...

The locus coeruleus is a nucleus in the pons that plays important roles in homeostasis, arousal and sleep, memory and emotions. Neurons of the locus coeruleus project to numerous brain areas including ...

Tau aggregation begins not in the cortex, but in the brainstem. Does tangle deposition in the locus coeruleus, which often starts in a person’s 30s, presage Alzheimer’s disease? In the September 22 ...

Life may unfold as a continuous stream, but our memories tell a different story. We do not recall the past as one long, unbroken text. Instead, we remember it as a series of meaningful events, like ...

A small region deep in the brain might be "ground zero" for Alzheimer's disease, suggest the authors of a new review of scientific literature. It's still early to know for sure, though. University of ...

The locus coeruleus is a region of the brain that is instrumental in coordinating our mental processing and is the primary source of noradrenaline in the brain, which acts to regulate arousal states ...