Global pediatric data suggest resistance to last-line antibiotics is climbing fast, with ICU and sepsis cases showing some of ...

Multidrug resistance in cancer can be overcome by combining a drug that blocks a key enzyme with another anticancer drug, according to a study in preclinical models led by researchers at UT ...

Fostemsavir is associated with maintained viral suppression in many heavily treated patients with multidrug-resistant HIV.

As multidrug antibiotic resistance emerges as a potent public health challenge, medical science has renewed attention on the ...

The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is described in Nature. The drug, named mandimycin, is a member of a known family of ...

The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel modes of action are urgently needed.

Multi-drug resistance (MDR) remains the most formidable pharmacological barrier to effective cancer chemotherapy, accounting ...

Multidrug resistance (MDR) remains a major obstacle to effective pharmacotherapy in cancer, infectious diseases and central nervous system disorders. Resistance often arises through elevated activity ...

Multidrug-resistant organisms (MDROs) are a major challenge in everyday medical practice, as they often cannot be treated with antibiotics. According to the Robert Koch Institute, there are 400,000 to ...

Scientists at the University of Liverpool, working with international collaborators, have discovered Novltex, a groundbreaking new class of antibiotics with potent activity against some of the world's ...

Suggested Citation: "2 The Global Spread of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis." Institute of Medicine. 2009. Addressing the Threat of Drug-Resistant Tuberculosis: A ...