Stanford Medicine investigators have replicated, in a lab dish, one of humans' most prominent nervous pathways for sensing pain. This nerve circuit transmits sensations from the body's skin to the ...

When a house catches on fire, we assume that a smoke alarm inside will serve one purpose and one purpose only: warn the ...

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate ...

This study focused on how NMDAR, an important cell surface receptor, triggers a complex chemical cascade in postsynaptic neurons in the nucleus accumbens region of the brain. More specifically, the ...

Kallyope, a late-stage biotechnology company leveraging unique insights into neural signaling pathways to develop innovative therapies for migraine and metabolism, today announced positive results ...

Researchers have identified a promising new strategy for treating alcohol use disorder (AUD). A novel study found that the dopamine-boosting drug tolcapone increases activity in the prefrontal cortex ...

Kallyope, a late-stage biotechnology company leveraging unique insights into neural signaling pathways to develop innovative therapies for health challenges faced by hundreds of millions of people ...

Advancing elismetrep, a novel oral TRPM8 antagonist, towards pivotal studies for the acute treatment of migraine, a disease that affects 1 in 6 adults in the U.S.Progressing K-554, a potential ...