Notre Dame (8-2) is favored by more than five touchdowns over Syracuse, which is the first of two 3-7 teams remaining on the Irish's schedule (which concludes Nov. 29 at Stanford).By winning out, Notre Dame should make the playoff and also would be a solid contender to play host to a first-round game for the second consecutive year as a top-eight team.

Marcus Freeman and the 9th-ranked Notre Dame Fighting Irish face their biggest test of the Atlantic Coast Conference season Saturday afternoon against the No. 22 Pittsburgh Panthers.

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It's Notre Dame vs. Pittsburgh in Week 12 of the college football season. Follow along for live score updates from Acrisure Stadium in Pittsburgh, Pa.

Two of the best programs in college basketball will clash on Friday as No. 24 Notre Dame hosts No. 11 USC. Notre Dame has fallen short of expectations under head coach Niele Ivey, failing to advance past the Sweet 16 in each of the past four seasons.

The No. 11 USC Trojans face the No. 24 Notre Dame Fighting Irish on Friday, Nov. 21, 2025 at Purcell Pavilion in South Bend, Ind.