In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning ...

A 58-year-old woman presents to the hospital reporting fatigue, swelling of the legs and feet, and shortness of breath. She explains that her symptoms have been getting worse over the past 2 months.

A 28-year-old man who is new to your list, and whose records have not yet arrived, presents in your emergency surgery with a two-day history of substernal chest pain. He describes this as sharp and ...