XPD/Rad3-like helicases are critical enzymes for preserving genomic integrity across various organisms 1,2,3,4,5. These superfamily 2 helicases translocate 5ˈ to 3ˈ along ssDNA and unwind DNA/DNA and ...

The alternative text for this image may have been generated using AI. Fig. 3: Structural studies of free and DNA-bound UBP. The alternative text for this image may have been generated using AI. While ...

D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription factor and other regulatory proteins.

Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes ...

A new analysis of research into the most common type of breast cancer has zeroed in on an overlooked hormone that may be responsible for the increased risk of breast cancer death in postmenopausal ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

This article is based on a poster originally authored by Sunidhi Shetty, Narasimha Murthy Bandaru, Anna Moberg and Marco Manni, which was presented at ELRIG Drug Discovery 2024 in affiliation with ...

DNA is composed of long chains that act as the blueprint for living organisms. In genetic engineering, scientists cut DNA at ...