The first randomized controlled trial in the U.K. has found that a single dose of psilocybin, the active compound found in "magic mushrooms," produced significant improvements in depression compared ...

With a bit of creativity, evidence can be drawn from data we already have in the form of natural experiments, write ...

Of the 58 participants enrolled, 47 completed the initial comparison between a one-month ketogenic diet intervention and a diet-as-usual control group. Twenty-five participants opted to continue the ...

Introduction We sought to evaluate preliminary efficacy and implementation outcomes of an e-cigarette and tobacco cessation intervention for hospitalised youth in the USA. Methods We conducted a pilot ...

A landmark clinical trial of nearly 4,000 babies has found that acetaminophen and ibuprofen are equally safe to use during a ...

In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In RCTs, researchers create randomly assigned treatment and control groups, ...

Oxaliplatin-Based Versus Alkylating Agent in Neuroendocrine Tumors According to the O6-Methylguanine-DNA Methyltransferase Status: A Randomized Phase II Study (MGMT-NET) The median time post-HCT was ...

This systematic evaluation of 54 target trial emulation studies in oncology examines their study characteristics, key protocol components, and consistency with corresponding randomized controlled ...

Phase III randomized placebo-controlled trial on repurposing olanzapine for prevention of radiotherapy-induced nausea and vomiting (RINV): CTRI/2022/01/039723. PNQ ≥D 3 months after end of PTX 32.0% ...

Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic ...