In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

Protein sequence design is critically important for protein engineering. Despite recent advancements in deep learning-based methods, achieving accurate and robust sequence design remains a challenge.

Computational protein design has emerged as a powerful tool for rational protein design, enabling significant achievements in the engineering of therapeutics 1,2,3, biosensors 4,5,6, enzymes 7,8, and ...

National Cancer Institute researchers have developed a method called HORNET for characterizing 3D topological structures of large and flexible RNA molecules. Scientists used atomic force microscopy ...

A graphic representation of a round, lumpy, blue protein and a single, comblike, purple strand of RNA interacting with a twisted, double, blue strand of DNA that separates where it meets the RNA. A ...

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...