While proteomic analysis enables scientists to explore what goes awry in Alzheimer’s disease, most studies have focused on brain tissue, cerebrospinal fluid, or plasma, or on sporadic versus familial ...

Inhalation of aerosols containing Legionella bacteria can result in a common severe form of pneumonia called Legionnaires’ disease. Study: Vehicle Windshield Wiper Fluid as Potential Source of ...

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies (GWAS) can contribute to sporadic Parkinson's disease (PD) ...

In frontotemporal dementia, degeneration of neurons in the frontal and temporal lobes of the brain leads to impairments in ...

August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

How alike are familial and sporadic Alzheimer’s? It depends. Broadly speaking, in terms of their presymptomatic biomarker changes, the two resemble each other closely (see Feb 2024 news). In terms of ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to reveal disruptions in gene function in three brain regions of patients with ...

In patients with sporadic Creutzfeldt–Jakob disease, pathologic disease-associated prion protein (PrP Sc) has been identified only in the central nervous system and olfactory-nerve tissue.

People who died with sporadic Creutzfeldt-Jakob disease were more likely to have been prescribed antidepressants before neurologic symptoms started, a retrospective study in Austria showed. Compared ...

A new sporadic prion protein disease has been discovered. Variably protease-sensitive prionopathy (VPSPr), as it has been named, is the second type of complete sporadic disease to be identified since ...