Severe physical injury provokes an immediate and complex reaction of the innate immune system, characterised by the release of damage-associated molecular patterns, the rapid activation of neutrophils ...

Investigators created a model for predicting the risk of urinary sepsis after endoscopic surgery for urinary stones using several key variables. A model incorporating values of stone composition and ...

Severe alopecia areata is associated with elevated systemic inflammatory markers, which decrease with JAK inhibitor therapy, suggesting broader immune activation. The study identified higher levels of ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

A recent study revealed that periodontitis reprograms bone marrow neutrophils through a Chac2-driven glutathione metabolic pathway, promoting a highly inflammatory N1 state that fuels systemic ...