Innate immunity constitutes the body’s first line of defence against infection and tissue disruption. It relies on physical barriers such as skin and mucosa, cellular sentinels including neutrophils, ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways—ways that have important implications for the development of ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

All cellular life—from humans to bacteria—possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but ...