When cells in the body die, they release DNA. This DNA, known as cell-free DNA (cfDNA), makes its way into the bloodstream where it gets chopped up by enzymes, and in minutes to hours, the liver pulls ...

Androgen pathway gene expression and response to hormonal therapy in prostate cancer (SWOG S1216). This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include ...

Researchers found that maternal plasma cell-free DNA methylation patterns in late pregnancy were associated with later autism ...

Small cell lung cancer (SCLC) remains a challenging cancer type to treat effectively. While patients initially respond to chemotherapy and immunotherapies, the disease almost always returns, often ...

Use of a standardized cell-free (cf)DNA-sequencing and cancer-screening protocol detected cancer in nearly half of pregnant or postpartum women who initially received unusual or nonreportable clinical ...

A novel, blood-based test developed using fragmentomic features of cell-free DNA (cfDNA) detects colorectal cancer (CRC) with a 90.4% sensitivity and shows consistent performance across stages and ...

Findings from a study published in Nature Medicine show that donor-derived cell-free DNA (dd-cfDNA), also called liquid biopsy, has the potential for early detection of kidney transplant rejection.

Liver transplant is a lifesaving surgery, but a significant number of patients experience organ rejection or other complications. A study by scientists at Georgetown University and MedStar Health has ...

A key obstacle in isolating cfDNA is the intricate, labor-intensive manual process required by existing protocols to extract it for downstream processing. This article introduces a unique automated ...