The Rams and 49ers open their seasons in the NFL's first-ever game in Australia. Will Tullos / The Athletic; Sean Gardner, Ezra Shaw / MELBOURNE, Australia — On Tuesday night, the Los Angeles Rams embarked on one of the most uncommon international journeys the NFL has seen.

The Los Angeles Rams face a tougher matchup with George Kittle off the San Francisco 49ers’ injury report for NFL Week 1 game.

The Rams have the personnel and scheme to take down the 49ers in Australia. They just need to execute and accomplish these five things.

‘There’s red everywhere’ one Australian Niners fan told SI. The Rams, in contrast, have made it a short trip.

The 49ers and Rams meet Thursday night in Melbourne, Australia. Athlon Sports asks readers what they think will happen.

The 49ers' final injury report lists DT James Thompson Jr. as questionable for Week 1 vs. the Rams, while Alfred Collins and Aaron Donald are out.

As the San Francisco 49ers and Los Angeles Rams are preparing to face one another in a Week 1 matchup in Australia, it appears the rivalry has levels to it as it’s gone beyond the football field and into the media.

The 49ers and Rams are relatively healthy after all entering their matchup in Australia.