Huntington’s disease (HD) is caused by an expansion of a short DNA sequence — the letters C-A-G — located in the very first ...

In people with premanifest HD, lower scores on the visual thinking tests were linked with more movement changes over time.

A new Phase 1 study is testing SRP-1005, a huntingtin-lowering therapy given by injection under the skin. It’s early days, but this approach could add an important new arrow to the HD drug development ...

Spark and Roche issued a joint community letter to share that the first patient has been dosed in a new HD gene therapy trial. To capture your interest with a romance, let’s talk about how these ...

In plain language. Written by scientists. August was another busy month for HD research! Learnings from past trials, new approaches to huntingtin lowering, the start of INSIGHTT and PRECISE-HD, three ...

After receiving a high dose of uniQure’s gene therapy for Huntington’s disease, a few patients experienced serious side effects, but are now recovering. HDBuzz explores what this means for the ...

August has been a packed month for Huntington’s disease (HD) research. We’ve looked at what can be learned from disappointing ...

People who develop Huntington’s disease (HD) are born with the genetic change that causes the disease. So why does it take decades, usually around 40 to 50 years, for the symptoms of the disease to ...

First to speak was Aikaterini Papadopoulou, who talked about her work targeting a fragment of the expanded HTTHTT one abbreviation for the gene that causes Huntington’s disease. The same gene is also ...

This week, we heard an update from Roche about their huntingtin-lowering therapy, tominersen, currently being tested in the GENERATION HD2 trial. An independent data monitoring committeemonitoring ...

Wave Life Sciences shared the disappointing news that their two ASOs in Phase 1/2 trials in HD patients did not successfully lower mutant huntingtin. Unfortunately, in the PRECISION-HD trials, there ...

For those who were following the live tweets from HDBuzz about the CHDI HD Therapeuticstherapeutics treatments Conference or tuned in to the HDSA Convention, we may have caught your attention with the ...