The type I CRISPR protein Cas3 works like Pac-Man, chomping away at a continuous stream of nucleotides with intrinsic activity for introducing targeted large deletions from a few hundred base pairs to ...

Duchenne muscular dystrophy (DMD) is a muscle degeneration disorder caused by mutations affecting the dystrophin gene. Researchers show how a dual CRISPR RNA method restored dystrophin protein ...

The CRISPR gene-editing system is one of the most important medical breakthroughs of recent years, but that doesn't mean it's perfect. The most common enzyme in use is Cas9, which acts like a pair of ...

Researchers at North Carolina-based Locus Biosciences think they have a potential cure for antibiotic resistance using CRISPR’s lesser-known Cas3 enzyme. Most of the interest in CRISPR technology ...

Design by Evelyn Mousigian. Buy this photo. The CRISPR-Cas3 system, the focus of the U-M paper, is much less researched than Cas9. Despite this, Rackham student Mason Myers, one of the lead authors on ...

ITHACA, N.Y. - A Cornell researcher, who is a leader in developing a new type of gene editing CRISPR system, and colleagues have used the new method for the first time in human cells - a major advance ...

With further optimization and safety evaluation, this CRISPR–Cas3 can be established as a new and safer platform for genome-editing-based therapies, providing patients with durable, possibly one-time ...

In a recent study published in Stem Cell Reports, researchers evaluated the use of a dual clustered regularly interspaced short palindromic repeats (CRISPR)-Cas3 system for inducing multi-exon ...

Antibiotic resistance is one of the biggest potential threats to global health today. But Locus Biosciences is hoping that their crPhage technology might provide a new solution. Based in North ...

Scientists have used a new type of gene editing CRISPR system for the first time in human cells - a major advance in the field. A Cornell researcher, who is a leader in developing a new type of gene ...