During gastrulation, sequentially lineage-restrictive mesodermal cell populations emerge along a developmental trajectory involving primitive streak to lateral mesoderm formation, followed by cardiac ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

hiPSC cardiac differentiation was done by modulation of the WNT/β-catenin pathway with the GSK3 inhibitor CHIR99021 to induce mesoderm differentiation and spatial organization on the PEG. Increased ...