Developing treatments for rare diseases poses many unique challenges that cannot be addressed by traditional study designs. Small populations will result in prolonged enrolment periods and/or ...

Once you have determined your research question, the next step is to decide on a research design. As random assignment tends to be challenging in SoTL, most projects tend to fall into the ...

Case-cohort study designs represent a cost-effective and efficient strategy for analysing time-to-event data, particularly when the event of interest is rare. By selecting a random subcohort along ...

As biomarker studies employ increasingly complex and expensive genomics and other correlative methods, it is increasingly important to rigorously design these studies and analyze the downstream ...

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

We study design in all its manifestations, with a focus on its implications. Do you care about design and its impact on the individual, society, and the environment? Are you interested in honing your ...