The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

Kyle Shanahan and the San Francisco 49ers are rallying around Trent Williams and Charvarius Ward after the NFL stars both ...

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but he will miss ...

The 49ers running back, the reigning NFL offensive player of the year, is facing a six-week recovery for a knee injury.

The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

San Francisco 49ers star running back Christian McCaffrey is out for the rest of 2024 after suffering a significant knee ...

The Los Angeles Rams' bitter rival suffered yet another devastating injury during their Week 13 road loss against the Buffalo ...

The San Francisco 49ers suffered another disappointing loss on Sunday night as they took on the Buffalo Bills on the road in ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

San Francisco 49ers running back Christian McCaffrey could be done for the season after just four games. As head coach Kyle ...

ORCHARD PARK, N.Y. (AP) — San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan ...

The San Francisco 49ers received some brutal news on Sunday evening. According to head coach Kyle Shanahan, running back ...