The first real test for each team. The matchup was announced 10 years ago and will be Mississippi State’s first visit to the state of Minnesota and first regular-season game against a Big Ten team since 1980. Illinois won at Duke 45-19 last season and easily handled UAB in its 2026 opener.

Oklahoma Sooners vs Michigan Wolverines Game Preview

Greg McElroy predicts the Oklahoma Michigan Week 2 showdown, picking a winner and final score. Here is his reasoning plus what both teams bring to Ann Arbor.

The Wolverines went from a slight favorite to a nearly full-possession underdog after Saturday's Hail Mary win over Western Michigan.

Michigan's defense has a tall task on Saturday afternoon — containing dual-threat Oklahoma quarterback John Mateer. In a 24-13 win over Michigan last season, Mateer threw for 271 yards, rushed for 74 with one passing touchdown and two rushing scores.

Michigan center Jake Guarnera says the offensive line must improve to handle Oklahoma's talented defense.

And these are two of the biggest powerhouses of the SEC and the Big Ten. I’m excited. It’s going to be fun.” Michigan has more wins than any college program. Oklahoma ranks sixth in that category. Michigan has 10 national championships,

Kyle Whittingham warns that Brent Venables has built a multi-dimensional threat, highlighting a dominant defensive front and dual-threat quarterback John Mateer as primary dangers for the Wolverines