NFL picks, predictions for Week 1: Experts split on Patriots-Seahawks, Rams-49ers

Our NFL staff makes picks for every Week 1 NFL game. From Patriots-Seahawks to Broncos-Chiefs, here's a look at the biggest games.

Patriots vs Seahawks prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

New England Patriots vs Seattle Seahawks Game Preview for the 2026 NFL Regular Season Opener

Patriots vs. Seahawks predictions, odds, time: 2026 NFL kickoff game picks by model on 53-37 run

The SportsLine projection model has revealed its New England vs. Seattle picks for the NFL Kickoff Game 2026 on Wednesday

Experts adjust Patriots vs. Seahawks prediction after key roster updates on both sides of the ball

Get expert picks and score predictions for the Patriots vs. Seahawks Week 1 opening game. Breakdown of spread, odds, and game analysis from MassLive.

Seahawks-Patriots keys: Sam Darnold painting in his mind; secondary issues

And: Can coach Mike Macdonald’s Seattle defense again throttle New England’s run game as it did in Super Bowl 60? A Patriots rusher is out.

Patriots' Henderson, Seahawks' Okada ruled out for SB rematch

Patriots running back TreVeyon Henderson won't play in the regular-season opener against the Seahawks, while the defending Super Bowl champions may have to begin their title defense without two of their top three safeties.

Sam Darnold And The New-Look Seahawks Offense Face Huge Immediate Test

New OC Brian Fleury's acclimation is one of the top storylines for the Seahawks, who open the NFL season Wednesday against the Patriots.

What channel is Seahawks vs. Patriots on? Time, TV schedule, live stream to watch 2026 NFL season opener

What channel is Seahawks vs. Patriots on? Time, TV schedule, live stream to watch 2026 NFL season opener originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. The 2026 NFL season opens with a Super Bowl rematch between the Seahawks and Patriots.