Huntington’s disease (HD) is caused by an expansion of a short DNA sequence — the letters C-A-G — located in the very first ...

In plain language. Written by scientists. August was another busy month for HD research! Learnings from past trials, new approaches to huntingtin lowering, the start of INSIGHTT and PRECISE-HD, three ...

In people with premanifest HD, lower scores on the visual thinking tests were linked with more movement changes over time.

August has been a packed month for Huntington’s disease (HD) research. We’ve looked at what can be learned from disappointing ...

In plain language. Written by scientists. A new Phase 1 study is testing SRP-1005, a huntingtin-lowering therapy given by injection under the skin. It’s early days, but this approach could add an ...

A new study from researchers at the University of Washington and University College London explores different ways to lower the huntingtin proteinhuntingtin protein The protein produced by the HD gene ...

In plain language. Written by scientists. Scientists discover a rare genetic quirk that may extend the age of onset in people with Huntington’s disease by boosting cellular cleanup. A trial tested ...

In plain language. Written by scientists. Scientists engineered stem cells with “interrupted” CAG repeats to break up the toxic stretch. This may stop expansion, and could improve problems in cells ...