Improving imaging-based response after neoadjuvant chemotherapy (NAC) in breast cancer assessment could obviate histologic confirmation of pathologic complete response (pCR) and facilitate ...

Inflammatory bowel diseases (IBDs) in humans are characterized in part by aberrant CD4-positive (CD4+) T-cell responses. Currently, identification of foci of inflammation within the gut requires ...

We present an overview of our prospective fibroblast-activation protein inhibitor (FAPI) registry study across a 3-y period, with head-to-head comparison of tumor uptake in 68Ga-FAPI and 18F-FDG PET, ...

CD70-Targeted Immuno-PET/CT Imaging of Clear Cell Renal Cell Carcinoma: A Translational Study SNMMI Procedure Standard/EANM Practice Guideline for Brain [18 F]FDG PET Imaging, Version 2.0 ...

Personalized dosimetry with high accuracy is becoming more important because of the growing interest in personalized medicine and targeted radionuclide therapy. Voxel-based dosimetry using dose point ...

SPECT is used to quantitatively and visually assess the distribution of radioactive biologic markers (tracers) in vivo in order to, for example, study animal models of disease and test new ...

Introduction: Positron emission tomography (PET) is an imaging procedure that utilizes radiotracers to identify diseases and monitor their progression. Its ability to provide constructive assessments ...

When pregnancy is discovered during or after a diagnostic examination, the physician or the patient may request an estimate of the radiation dose received by the fetus as per guidelines and standard ...

WHY IS FAP-TARGETED THERAPY ATTRACTIVE? FAP-positive CAFs are found in more than 90% of epithelial cancers, therefore representing a potential pan-cancer target (6). Targeting FAP to deplete stromal ...

The diagnosis and management of breast cancer are undergoing a paradigm shift from a one-size-fits-all approach to an era of personalized medicine. Sophisticated diagnostics, including molecular ...

In the tubules of the kidney, small proteins and polypeptides are reabsorbed after glomerular filtration. An important mechanism of reabsorption is uptake via megalin, a 660-kDa transmembrane ...

Quantitative dynamic PET with compartmental modeling has the potential to enable multiparametric imaging and more accurate quantification than static PET imaging. Conventional methods for parametric ...