India’s recent HIV rise highlights prevention gaps, while twice-yearly lenacapavir could offer a highly effective, convenient ...

The position is under the supervision of the Principal Investigator, Dr Donna McNeale, and is embedded in the Biohybrid Materials Group headed by Professor Mauri Kostiainen.

ABSTRACT: Helicobacter pylori remains a major public health challenge in Kenya, where persistently high infection rates, socioeconomic vulnerabilities, and limited diagnostic capacity contribute to ...

A research group has successfully determined, for the first time in the world, the capsid (outer shell) structure of Melbournevirus—a member of the giant virus family—at a resolution of 4.4 Å using ...

Melbournevirus is an icosahedral giant virus with a diameter of approximately 250 nm. It is covered by capsid proteins composed of MCP and mCP, and it contains a folded DNA genome with characteristic ...

New hollow dodecahedral shell demonstrates remarkable stability and potential for functionalization and encapsulating macromolecules. (Nanowerk News) Controlling the topology and structure of ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a ...

Separating full and empty adeno-associated virus (AAV) capsids during the manufacture of single-gene therapies remains a significant challenge. Ultracentrifugation and anion exchange chromatography ...

Once perceived as mere pathogens, adenoviruses have transformed remarkably, becoming indispensable allies in the fight against genetic disorders. In an era where medical innovation is paramount, ...

The first atom-level model of a DNA-packed viral capsid reveals genome structure and possible new drug targets, University of Illinois researchers report. Pictured, from left: physics professor ...

University of Chicago researchers have discovered how HIV’s capsid structure enables the virus to enter a cell’s nucleus, providing new insights into the virus’s replication mechanism and potential ...