Glutamate levels increase in early psychosis but normalize over time, challenging established perspectives on schizophrenia progression. The study involved treatment-naive patients, isolating natural ...

Researchers are uncovering how disrupted glutamatergic synapses drive diverse forms of intellectual disability, revealing new ...

Stress, the body's natural response to different types of challenges and daily problems, is an inherently harmless state ...

To study how a key chemical neuromodulator affects signaling in the brain's cortex, Garrett Neske, PhD, has received a three-year, $300,000 grant from the Whitehall Foundation, a nonprofit ...

Depression, one of the most prevalent mental health disorders worldwide, is characterized by persistent feelings of sadness, ...

Summary: Autistic adults show reduced availability of a key glutamate receptor, mGlu5, across widespread brain regions. This difference supports the theory that an imbalance between excitatory and ...

Summary: New research shows that astrocytes play an active role in nicotine-induced brain changes, challenging the long-held neuron-centered view of addiction. Nicotine stimulates receptors on ...

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system. After exocytotic release from presynaptic nerve terminals, glutamate diffuses across the synaptic cleft and ...

Seizures in people with multiple sclerosis (MS) may be driven by changes in levels of certain brain signaling molecules, implying that targeting these molecules may be a viable strategy to treat ...

A preclinical study by biomedical scientists at the University of California, Riverside, has shown why some people with multiple sclerosis, or MS, also suffer from seizures — a debilitating ...

Lower levels of the inhibitory neurotransmitter GABA in the posterior insula were significantly associated with neuropathic pain in people with HIV, suggesting a potential role for the GABAergic ...