The FOX NFL Kickoff Crew play Fill in the Blank and discuss the biggest storylines going into the season, featuring the Seattle Seahawks' big win, the Los Angeles Rams' loss and more.

Broadcast and streaming information for the San Francisco 49ers Week 2 matchup against the Miami Dolphins at Levi's® Stadium.

SANTA CLARA — The San Francisco 49ers regrouped Wednesday for their first practice since returning home from Australia, and they packed more than a division win into their luggage. They brought home answers to two of their biggest questions.

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The San Francisco 49ers totally plowed through the Los Angeles Rams in their season opener in Australia with a 27-7 victory. But, heading into Week 2, they're dealing with a major injury on offense. On Wednesday,

NFL Week 2 score predictions, picks, betting odds for San Francisco 49ers vs Miami Dolphins game Sunday, Sept. 20, 2026. Who will win Week 2 NFL game?