For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and ...

Biology textbooks explain that cells follow a universal rule when processing gene transcripts to make proteins. Non-coding snippets of RNA are bracketed by a guanine-thymine (GT) nucleotide sequence ...

HIV-seq identifies key differences in HIV-infected cells before and after starting antiretroviral therapy to support treatment research.

Marlene Belfort does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Scientists in the laboratory of Rendong Yang, Ph.D., associate professor of Urology, have developed a new large language model that can interpret transcriptomic data in cancer cell lines more ...

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning algorithms, ClairS-TO and Clair3-RNA, that significantly advance genetic ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

A total of 68,579 cells from LUAD patients revealed heterogeneous transcriptomic profiles of AT2 tumor cells and facilitated the identification of cancer cell subtypes that deviated from the normal ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine.

Researchers have sequenced the oldest RNA ever recovered, taken from a woolly mammoth frozen for nearly 40,000 years. The RNA reveals which genes were active in its tissues, offering a rare glimpse ...