The replication crisis in psychology refers to concerns about the credibility of findings in psychological science. The term, which originated in the early 2010s, denotes that findings in ...

One is that the DNA template somehow becomes defective during replication, and causes the polymerase to pause (Figures 3 and 4a). For example, a DNA base can be chemically modified or ...

However, conditions for DNA replication are rarely ideal. For example, environmental toxins or drugs cause DNA damage and interfere with DNA replication. How does a cell circumvent such problems?

Researchers have uncovered a source of "replication stress" during DNA replication, shedding light on a new cancer target.