SportsLine's advanced model has locked in its Week 1 NFL predictions today from 10,000 simulations

Week 1 usually comes with the obvious storylines. New quarterbacks, big-name rookies, and teams carrying Super Bowl expectations tend to dominate the conversation; however, some of the more important developments can be hiding underneath that noise.

Depending on where you look, Caleb Williams is either a superstar already or on the verge of becoming one.

Welcome to the 2026 NFL season. In this article, each week we will focus on a few key matchups where the underdog looks primed to shock the league with an upset victory. Week 1 is

Sean McVay brings an undefeated international record to Australia as Matthew Stafford and Myles Garrett lead the Rams against the 49ers in Week 1

What should we expect from Patrick Mahomes? How will the Raiders handle their QB situation? Which receivers could break out? Our insiders have Week 1 intel.

Bears receive major injury boost ahead of Week 1.

The first week of the 2026 NFL season is underway, and some managers may already find themselves in catch-up mode. Fortunately, there's still time to adjust lineups and seek help on the waiver wire before the bulk of the schedule unfolds on Sunday.