San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after suffering a PCL injury in

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling playoff hopes for the San Francisco 49ers. A season that began with the Niners as one of the favorites to get back to the Super Bowl has reached what appears to be rock bottom after a 35-10 loss in the snow at Buffalo on Sunday night in a game McCaffrey left early with a knee injury that

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve. McCaffrey left the snowy field in Buffalo on Sunday night after a 5-yard gain that was preceded by him heading to the sideline in apparent pain at the end of an 18-yard run.