A gene-edited pig kidney kept a patient with end-stage kidney disease dialysis-free for 271 days, then failed and was removed without leaving the recipient sensitised against human donors. Eighty-two ...
Delivering CRISPR-Cas9 as mRNA in lipid nanoparticles preserved the fitness and erythroid potential of edited human ...
Global adoption growing with more than 400 institutions across 33 countries ordering DNA constructs up to 49.1 kb, with ...
(Nasdaq: ACET), a clinical stage biotechnology company discovering and developing allogeneic gamma delta CAR T cell and in ...
–ARIA investment advances QBI's landmark Science study, accelerating the path from molecular discovery to new precision ...
An new end-to-end nomination workflow improves the nomination of genomic sites that may be unintentionally edited by CRISPR-Cas, combining high analytical sensitivity with a comparatively manageable ...
Lyell Immunopharma is a clinical-stage biotechnology company focused on the development of CAR T-cell therapies to advance their use in cancer treatment. The company has developed multiple genetic and ...
Emerging from stealth, Kindred announces peer-reviewed results in The CRISPR Journal, demonstrating the creation of two healthy beagles with a targeted CRISPR-Cas9 edit that eliminates the major dog ...
A six-year-old girl died after receiving an experimental CRISPR-Cas base-editing treatment for a nonfatal neurodevelopmental disorder in China. The fatal immune reaction followed preclinical safety ...
Delivering CRISPR-Cas9 as mRNA in lipid nanoparticles preserved the fitness and erythroid potential of edited human haematopoietic stem and progenitor... Clinical: Single CRISPR Infusion Keeps Lipids ...
A new artificial intelligence–guided strategy can design highly divergent yet functional variants of TnpB, a compact RNA-guided nuclease that is evolutionarily related to CRISPR-Cas12 enzymes. By ...
A search for new CRISPR enzymes to improve crop breeding has unexpectedly led to a new strategy for selectively eliminating cancer cells. The story highlights how discoveries originating in ...
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